Crescentic Glomerulonephritis in IgA Multiple Myeloma: A Case Report

BACKGROUND There are few reports of glomerulonephritis (GN) with crescents and a rapidly progressive course that lead to a diagnosis of a previously unsuspected B-cell dyscrasia. CASE PRESENTATION We report a case of rapidly progressive GN: the patient showed no evidence of etiology at the time of biopsy and was diagnosed as IgA multiple myeloma (MM) during investigation based on a renal biopsy. He presented diffuse proliferative and exudative GN and marked plasma cell infiltration of the kidney. CONCLUSION The present case raises the possibility that proliferative GN with crescents may be a rare mode of presentation of MM.